Effects of chronic SCH 23390 or acute EEDQ on the discriminative stimulus effects of SKF 38393.

@article{Cao1992EffectsOC,
  title={Effects of chronic SCH 23390 or acute EEDQ on the discriminative stimulus effects of SKF 38393.},
  author={Guoqing Cao and Bruce D. Perry and William L. Woolverton},
  journal={Pharmacology, biochemistry, and behavior},
  year={1992},
  volume={41 2},
  pages={321-7}
}
Three groups of rats (n = 8/group) were trained in a two-lever, food-reinforced drug discrimination paradigm to discriminate the D1 agonist SKF 38393 (SKF; 8.0 mg/kg, IP) from saline. After acquisition of the discrimination, the dose-response function for SKF (2.0-16 mg/kg, IP) was determined using a cumulative dosing procedure. In one group, the SKF dose… CONTINUE READING