Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study.

@article{L1997EffectsOC,
  title={Effects of chondroitinase ABC and chymopapain on spinal motion segment biomechanics. An in vivo biomechanical, radiologic, and histologic canine study.},
  author={Deyang L{\"u} and Yasuhiro Shono and Itaru Oda and Kuniyoshi Abumi and Kiyoshi Kaneda},
  journal={Spine},
  year={1997},
  volume={22 16},
  pages={1828-34; discussion 1834-5}
}
STUDY DESIGN The biomechanical effects of chondroitinase ABC and chymopapain related to spinal segmental instability were investigated using a canine model, as well by as radiologic and histologic analyses. OBJECTIVES To evaluate the biomechanical, radiologic, and histologic affects on the lumber intervertebral disc of chondroitinase ABC compared with chymopapain. SUMMARY OF BACKGROUND DATA No study on the biomechanical effects of chondroitinase ABC has been reported. METHODS Forty-eight… CONTINUE READING

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