Effects of chondroitin sulfate on brain response to painful stimulation in knee osteoarthritis patients. A randomized, double-blind, placebo-controlled functional magnetic resonance imaging study.

@article{Monfort2017EffectsOC,
  title={Effects of chondroitin sulfate on brain response to painful stimulation in knee osteoarthritis patients. A randomized, double-blind, placebo-controlled functional magnetic resonance imaging study.},
  author={J. Monfort and J. Pujol and O. Contreras-Rodr{\'i}guez and J. Llorente-Onaindia and M. L{\'o}pez-Sol{\`a} and L. Blanco-Hinojo and J. Verg{\'e}s and M. Herrero and L. S{\'a}nchez and H. Ortiz and F. Monta{\~n}{\'e}s and J. Deus and P. Benito},
  journal={Medicina clinica},
  year={2017},
  volume={148 12},
  pages={
          539-547
        }
}
  • J. Monfort, J. Pujol, +10 authors P. Benito
  • Published 2017
  • Medicine
  • Medicina clinica
  • INTRODUCTION Knee osteoarthritis is causing pain and functional disability. One of the inherent problems with efficacy assessment of pain medication was the lack of objective pain measurements, but functional magnetic resonance imaging (fMRI) has emerged as a useful means to objectify brain response to painful stimulation. We have investigated the effect of chondroitin sulfate (CS) on brain response to knee painful stimulation in patients with knee osteoarthritis using fMRI. METHODS Twenty… CONTINUE READING
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