Effects of cholera toxin on in vitro models of immediate and delayed hypersensitivity. Further evidence for the role of cyclic adenosine 3',5'-monophosphate.

@article{Lichtenstein1973EffectsOC,
  title={Effects of cholera toxin on in vitro models of immediate and delayed hypersensitivity. Further evidence for the role of cyclic adenosine 3',5'-monophosphate.},
  author={Lawrence M. Lichtenstein and Christopher S. Henney and Henry R. Bourne and WilliamB. Greenough},
  journal={The Journal of clinical investigation},
  year={1973},
  volume={52 3},
  pages={
          691-7
        }
}
Cholera enterotoxin inhibits the antigen-induced. IgE-mediated release of histamine from human leukocytes and the lysis of allogeneic mastocytoma cells by splenic lymphocytes from specifically immunized mice. This effect requires a prolonged preincubation time of the toxin with the lymphocyte/leukocyte preparations: a demonstrable inhibition requires about 30 min of pre-incubation and the toxin activity is still increasing at 90-180 min. Cholera enterotoxin also stimulates adenyl cyclase and… CONTINUE READING

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Selective inhibition of fat cell response to cholera toxin ( CT ) and epinephrine ( E ) by blocking agents

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Quantitation of the cell - mediated immune response . I . The number of cytolytically active mouse lymphoid cells by immunization with allogeneic mastocytoma cells

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