Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum.

@article{Yayon1984EffectsOC,
  title={Effects of chloroquine on the feeding mechanism of the intraerythrocytic human malarial parasite Plasmodium falciparum.},
  author={Avner Yayon and Rina Timberg and Suzan Friedman and Hagai Ginsburg},
  journal={The Journal of protozoology},
  year={1984},
  volume={31 3},
  pages={367-72}
}
Ultrastructural investigations of P. falciparum cultivated in vitro in human erythrocytes revealed new features of the feeding mechanism of the parasite. Mature trophozoites and schizonts take up a portion of the host cytosol by endocytosis which is restricted to cytostomes and which involves the invagination of both parasitophorous and parasite membranes. The resulting endocytic vesicles, surrounded by two concentric membranes, migrate towards the central food vacuole membrane. The external… CONTINUE READING

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