Effects of chlorine on the decrease of estrogenic chemicals.

  title={Effects of chlorine on the decrease of estrogenic chemicals.},
  author={Byoung-Cheun Lee and Motoyuki Kamata and Yasushi Akatsuka and Makoto Takeda and Koichi Ohno and Tasuku Kamei and Yasumoto Magara},
  journal={Water research},
  volume={38 3},
The effects of chlorination on the elimination of three estrogenic chemicals such as 17beta-estradiol, nonylphenol and bis-phenol A were investigated using yeast two-hybrid assay (YTA), estrogen receptor (ER) competition assay (ER-CA), and high-performance liquid chromatography/mass spectrometry (LC/MS). The results of YTA, ER-CA and the analysis of LC/MS indicated that the estrogenic activity of the above-mentioned three endocrine disruptors were significantly reduced as a result of… CONTINUE READING

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