Effects of chlorinated amines on endothelial and epithelial barriers in vitro and ex vivo.

@article{Shasby1989EffectsOC,
  title={Effects of chlorinated amines on endothelial and epithelial barriers in vitro and ex vivo.},
  author={D. Michael Shasby and Frank Hampson},
  journal={Experimental lung research},
  year={1989},
  volume={15 3},
  pages={345-57}
}
Chlorinated amines are long-lived oxidants released from inflammatory cells. They have been observed to alter the function of important inflammatory molecules. Whether they can contribute directly to the inflammatory alteration of cellular barriers is not known. Monolayers of cultured porcine pulmonary artery endothelial cells, monolayers of cultured dog kidney tubular epithelial cells (MDCK), and the vascular surface of an isolated perfused rabbit lung were exposed to taurine chloramine… CONTINUE READING