Effects of chlorhexidine on proteolytic and glycosidic enzyme activities of dental plaque bacteria.
@article{Beighton1991EffectsOC, title={Effects of chlorhexidine on proteolytic and glycosidic enzyme activities of dental plaque bacteria.}, author={David Beighton and Joanne Decker and Karen A. Homer}, journal={Journal of clinical periodontology}, year={1991}, volume={18 2}, pages={ 85-9 } }
Chlorhexidine was tested for its ability to inhibit a wide range of glycosidic and proteolytic enzyme activities produced by Treponema denticola, Porphyromonas gingivalis, Bacteroides intermedius, Actinobacillus actinomycemcomitans, Capnocytophaga sputigena, Capnocytophaga gingivalis, Capnocytophaga orchracea, Capnocytophaga sp., Actinomyces viscosus, Streptococcus mitior, Streptococcus mutans, Streptococcus sobrinus, Streptococcus mitis, Streptococcus anginosus, Streptococcus oralis and…
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In vitro and ex vivo results suggest that wound healing devices which contain iodine, silver, chlorhexidine, and octenidine may add value to the antibacterial effect and also aid in chronic wound healing.
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Part of the effect of chlorhexidine in controlling caries progression in humans may be due to a decrease in the proteolytic activity of carious coronal and root dentin.
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Effects of CHX on the growth, morphology and proliferation of HGFs are investigated using human gingival fibroblasts and it is concluded that CHX only at the concentration of 0.002% does not interfere with HGF growth, that is so critical to wound healing.
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