Effects of chlorhexidine gluconate in drinking water on dental caries and oral microorganisms in the Syrian hamster.

@article{Fitzgerald1986EffectsOC,
  title={Effects of chlorhexidine gluconate in drinking water on dental caries and oral microorganisms in the Syrian hamster.},
  author={Robert J. Fitzgerald and David B Fitzgerald and Bethany Adams},
  journal={Archives of oral biology},
  year={1986},
  volume={31 10},
  pages={
          707-9
        }
}
Hamsters infected with Streptococcus sobrinus (formerly Streptococcus mutans) strain 6715-1119 were given high-sucrose diet 2000. After 5 days, they were presented with 0.05 or 0.1 per cent w/v chlorhexidine gluconate (CHX) continuously in their drinking water, which was well-tolerated. Compared to infected but untreated controls, their caries scores were less by 84 and 97 per cent respectively after 42 days. Coronal dental plaque deposits were reduced in a dose-related fashion. Culture plates… CONTINUE READING
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