Effects of chemotherapy-induced testicular damage on inhibin, gonadotropin, and testosterone secretion: a prospective longitudinal study.

@article{Wallace1997EffectsOC,
  title={Effects of chemotherapy-induced testicular damage on inhibin, gonadotropin, and testosterone secretion: a prospective longitudinal study.},
  author={Euan M Wallace and Nigel Patrick Groome and Simon C. Riley and Albert C. E. Parker and Fredrick C W Wu},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1997},
  volume={82 9},
  pages={3111-5}
}
To investigate the role of inhibin in the control of follicle-stimulating hormone (FSH) secretion, we have measured levels of immunoreactive inhibin (ir-inhibin), inhibin B, Pro-alpha C containing inhibins, FSH, luteinizing hormone (LH), and testosterone in twelve men with hematological malignancies before, during, and after chemotherapy. Inhibin B levels fell significantly by 1 month from a mean +/- SE baseline level of 273.2 +/- 32.8 pg/mL, reaching a nadir of 52.6 +/- 15.3 pg/mL at 4 months… CONTINUE READING

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