Effects of changes in brain 5-HT activity on indicators of cortical arousal.

@article{Rammsayer1988EffectsOC,
  title={Effects of changes in brain 5-HT activity on indicators of cortical arousal.},
  author={Thomas Rammsayer and Petra Netter},
  journal={International clinical psychopharmacology},
  year={1988},
  volume={3 3},
  pages={231-7}
}
Clinical studies on fluoxetine have reported occasional symptoms of increased fatigue in depressed patients. On the other hand, experimental studies in healthy subjects have demonstrated evidence for fluoxetine-induced increases in cortical arousal. The present placebo-controlled study with 24 healthy subjects was designed to answer the following questions: Does fluoxetine increase measures of cortical arousal and decrease feelings of alertness, and does the 5HT2 receptor blocker ritanserin… CONTINUE READING