Effects of centrally injected amylin on sexual behavior of male rats

@article{Clementi1999EffectsOC,
  title={Effects of centrally injected amylin on sexual behavior of male rats},
  author={Giuseppe Clementi and Lina Busă and Ernesto de Bernardis and Agatina Prato and Filippo Drago},
  journal={Peptides},
  year={1999},
  volume={20},
  pages={379-382}
}
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22 Citations
Background Citations
6
Results Citations
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22 Citations

Citation Type

Citation Type

Salmon Calcitonin Attenuates Some Behavioural Responses to Nicotine in Male Mice
TLDR
The present data reveal that activation of CTR or/and amylin receptors attenuates certain nicotine-induced behaviours in male mice, further contributing to the understanding of appetite-regulatory peptides in reward regulation.
Amylin infusion into rat nucleus accumbens potently depresses motor activity and ingestive behavior.
  • B. Baldo, A. Kelley
  • Biology, Psychology
    American journal of physiology. Regulatory, integrative and comparative physiology
  • 2001
TLDR
The Acb may be a target for behavioral regulation by satiety-related peptides like amylin, which exerts anorexic effects on central administration through infusions into Acb subregions and reduces motor activity in nondeprived rats tested in the absence of food or water.
Amylin causes anorexigenic effects via the hypothalamus and brain stem in chicks
Activation of amylin receptors attenuates alcohol‐mediated behaviours in rodents
TLDR
It is shown that acute sCT administration attenuated the established effects of alcohol on the mesolimbic dopamine system, particularly alcohol‐induced locomotor stimulation and accumbal dopamine release and that amylin receptor agonists could be considered for the treatment of alcohol use disorder in humans.
An amylin analogue attenuates alcohol-related behaviours in various animal models of alcohol use disorder
TLDR
It is shown that repeated sCT administration decreased alcohol and food intake in outbred rats, and data suggest that amylin signalling, especially in the NAc, may contribute to reduction of various alcohol-related behaviours.
Amylin activates distributed CNS nuclei to control energy balance
The glucagon-like peptide-1 receptor agonist, exendin-4, reduces sexual interaction behaviors in a brain site-specific manner in sexually naïve male mice
Antipsychotic-Like Actions of the Satiety Peptide, Amylin, in Ventral Striatal Regions Marked by Overlapping Calcitonin Receptor and RAMP-1 Gene Expression
TLDR
Whether intra-Acb amylin signaling modulates prepulse inhibition (PPI), a measure of sensorimotor gating deficient in several illnesses including schizophrenia, is investigated and AMY1-R may be a potential target for the development of putative antipsychotics or adjunct treatments that oppose metabolic side effects of current medications.
Facilitatory and inhibitory role of central amylin administration in the regulation of the gonadotropin-releasing hormone pulse generator activity in goats
Appetite-regulating peptides and natural rewards: emphasis on ghrelin and glucagon-like peptide-1
TLDR
Data support the emerging literature suggesting that ghrelin increases whereas GLP-1 decreases natural rewards, by showing that these peptides via reward-related areas modulate natural rewards from both the feeding-related and the social behavior domains of natural rewards.
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References

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Amylin increases cyclic AMP formation in L6 myocytes through calcitonin gene-related peptide receptors.
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