Effects of central osmotic stimulation on vasopressin and enkephalin release into the blood and cerebrospinal fluid and blood pressure.

@article{Ota1990EffectsOC,
  title={Effects of central osmotic stimulation on vasopressin and enkephalin release into the blood and cerebrospinal fluid and blood pressure.},
  author={Kyoko Ota and Toshifumi Kimura and Kentaro Matsui and K. Iitake and Masamichi Shoji and Michitoshi Inoue and Kazuo Sato and Minoru Ohta and Takeshi Yamamoto and Kaoru Yoshinaga},
  journal={Acta endocrinologica},
  year={1990},
  volume={122 1},
  pages={62-70}
}
To assess the central effect of hypertonic NaCl on the release of vasopressin (AVP) and methionine enkephalin-like substances into the blood and cerebrospinal fluid, and on blood pressure, ventriculocisternal perfusion (0.25 ml/min, 60 min) was performed in anesthetized dogs with artificial cerebrospinal fluid (CSF), either isotonic (300 mosmol/kg) or hypertonic (600 and 1200 mosmol/kg). The effect of central administration of a V1-AVP antagonist on the central osmotic challenge was also… CONTINUE READING