Effects of carotid body hypocapnia during ventilatory acclimatization to hypoxia.

@article{Dwinell1997EffectsOC,
  title={Effects of carotid body hypocapnia during ventilatory acclimatization to hypoxia.},
  author={Melinda R. Dwinell and P L Janssen and Jose Anselmo Arango Pizarro and Gerald E. Bisgard},
  journal={Journal of applied physiology},
  year={1997},
  volume={82 1},
  pages={118-24}
}
Hypoxic ventilatory sensitivity is increased during ventilatory acclimatization to hypoxia (VAH) in awake goats, resulting in a time-dependent increase in expired ventilation (VE). The objectives of this study were to determine whether the increased carotid body (CB) hypoxic sensitivity is dependent on the level of CB CO2 and whether the CB CO2 gain is changed during VAH. Studies were carried out in adult goats with CB blood gases controlled by an extracorporeal circuit while systemic (central… CONTINUE READING