Effects of carbon tetrachloride on albumin synthesis.

@article{Rothschild1972EffectsOC,
  title={Effects of carbon tetrachloride on albumin synthesis.},
  author={Marcus Adolphus Rothschild and Murray Oratz and Sidney S. Schreiber},
  journal={The Journal of clinical investigation},
  year={1972},
  volume={51 9},
  pages={
          2310-4
        }
}
The effects of CCl(4) on albumin synthesis were studied employing the isolated perfused liver. Carbonate-(14)C was used to measure newly synthesized albumin. 2.5 ml of CCl(4) was administered by stomach tube 2 hr before perfusion. Albumin synthesis decreased from 36 to 5 mg following the ingestion of CCl(4). Preperfusing the livers for 1 hr before measuring albumin synthesis resulted in an increase to 12 mg, and the addition of tryptophan to a final concentration of 10 mM resulted in a further… 
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References

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