Effects of carbon dioxide on tetanic contraction of frog skeletal muscles studied by phosphorus nuclear magnetic resonance.

@article{Nakamura1992EffectsOC,
  title={Effects of carbon dioxide on tetanic contraction of frog skeletal muscles studied by phosphorus nuclear magnetic resonance.},
  author={Tsuneyuki Nakamura and Kiyofumi Yamada},
  journal={The Journal of physiology},
  year={1992},
  volume={453},
  pages={
          247-59
        }
}
1. Bullfrog skeletal muscles were stimulated tetanically for 2 s at a sarcomere length of 2.4 microns in Ringer solution saturated with a gas mixture of O2 and CO2 of various proportions, at 4 degrees C. Using 31P nuclear magnetic resonance (31P-NMR), concentrations of inorganic phosphate (P(i)) and phosphocreatine (PCr) and intracellular pH (pHi) in whole muscle were measured in order to correlate the changes in these metabolites with the mechanical responses. 2. Resting muscles were first… CONTINUE READING
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