Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients.

@article{Leinonen1991EffectsOC,
  title={Effects of carbamazepine on serum antidepressant concentrations in psychiatric patients.},
  author={E Leinonen and Pirjo Lillsunde and V J Laukkanen and Pauli Ylitalo},
  journal={Journal of clinical psychopharmacology},
  year={1991},
  volume={11 5},
  pages={313-8}
}
The combination of carbamazepine and an antidepressant (doxepin, amitriptyline, mianserin) was given to 22 psychiatric inpatients with 29 measurements of their serum antidepressant concentrations. For comparison, sex-, age-, and dose-matched inpatients, treated with the antidepressant but not with carbamazepine, were selected as controls (N = 29). All the patients were treated with their routine daily dose for at least 7 days before the gas-chromatographic measurement of serum predose… CONTINUE READING