Effects of carbachol, cholecystokinin, and insulin on protein phosphorylation in isolated pancreatic acini.

@article{Burnham1982EffectsOC,
  title={Effects of carbachol, cholecystokinin, and insulin on protein phosphorylation in isolated pancreatic acini.},
  author={Dr. Daniel B. Burnham and John A. Williams},
  journal={The Journal of biological chemistry},
  year={1982},
  volume={257 17},
  pages={10523-8}
}
The role of protein phosphorylation in the regulation of pancreatic function by carbachol, cholecystokinin-octapeptide (CCK8), and insulin was investigated using isolated pancreatic acini of the mouse. Carbachol and CCK8 increased the phosphorylation of a Mr = 32,500 particulate protein and Mr = 16,000 and 23,000 soluble proteins. These agents also caused the dephosphorylation of Mr = 21,000 and 20,500 soluble proteins. Alterations in phosphorylation produced by carbachol were dose-dependent… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 17 extracted citations

Insulin Receptor

Maria Dolors Sans Gili, John A. Williams
2014

Pancreatic function in CCK-deficient mice: adaptation to dietary protein does not require CCK.

American journal of physiology. Gastrointestinal and liver physiology • 1999
View 1 Excerpt

Similar Papers

Loading similar papers…