Effects of calcium antagonists on lipids and atherosclerosis.

@article{Bernini1989EffectsOC,
  title={Effects of calcium antagonists on lipids and atherosclerosis.},
  author={Franco Bernini and Alberico L Catapano and Alberto Corsini and Remo Fumagalli and Rodolfo Paoletti},
  journal={The American journal of cardiology},
  year={1989},
  volume={64 17},
  pages={
          129I-133I; discussion 133I-134I
        }
}
The arterial accumulation of cholesterol and calcium is a hallmark of atherosclerosis. Calcium antagonists (CAs) lessen the severity of experimentally induced atherosclerosis in cholesterol-fed animals. The reduction of aortic cholesterol is one of the most striking findings. This effect is achieved without a reduction of plasma lipid or blood pressure, and is probably related to an interference of CAs with lipid metabolism in the arterial wall. To what extent these properties of CAs are due to… CONTINUE READING

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