Effects of calcitriol on phagocytic function, toll-like receptor 4 expression, and cytokine production of canine leukocytes.

@article{Jaffey2018EffectsOC,
  title={Effects of calcitriol on phagocytic function, toll-like receptor 4 expression, and cytokine production of canine leukocytes.},
  author={Jared A Jaffey and Juliana R Amorim and Amy E DeClue},
  journal={American journal of veterinary research},
  year={2018},
  volume={79 10},
  pages={
          1064-1070
        }
}
OBJECTIVE To determine the in vitro effects of calcitriol on indicators of immune system function in blood samples collected from healthy dogs. SAMPLE Blood samples from 8 healthy adult dogs. PROCEDURES Blood samples were incubated with calcitriol (10-7M) or control substance for 24 hours. Afterward, lipopolysaccharide (LPS)-, lipoteichoic acid (LTA)-, and N-acetylmuramyl-l-alanyl-d-isoglutamine hydrate (MDP)-stimulated leukocyte production of tumor necrosis factor (TNF) and interleukin-10… CONTINUE READING
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