Effects of calcitonin gene-related peptide on normal and atheromatous vessels and on resistance vessels in the coronary circulation in humans.

@article{Ludman1991EffectsOC,
  title={Effects of calcitonin gene-related peptide on normal and atheromatous vessels and on resistance vessels in the coronary circulation in humans.},
  author={Peter F. Ludman and Attilio Maseri and Patsy Clark and Graham J. Davies},
  journal={Circulation},
  year={1991},
  volume={84 5},
  pages={1993-2000}
}
BACKGROUND Calcitonin gene-related peptide (CGRP) is a potent dilator of normal epicardial coronary vessels in humans, but its effects on myocardial blood flow and atheromatous coronary vessel diameter are unknown. METHODS AND RESULTS Seven patients were entered for study of the effects of CGRP on coronary blood flow and 13 for the comparison of its effects on normal and atheromatous coronary arteries. In the first seven patients, left anterior descending artery (LAD) diameter at an… CONTINUE READING
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Coronary artery stenosis dilatation and hemodynamic effects of human - alpha calcitonin gene - related peptide in ischemic heart disease

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Atherosclerotic human coronary vessels preserve a dilator response to substance P in vivo

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