Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus).

Abstract

Retrospective analysis of data from a chronic (2-year) rat (Rattus norvegicus) carcinogenicity study was performed to compare the incidence of foot lesion development relative to cage type and animal supplier. Groups of rats from two different suppliers were housed in wire-bottom or polycarbonate cages. Clinical observations and body weights were collected… (More)

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