Effects of caffeine on muscle glycogen utilization and the neuroendocrine axis during exercise.

@article{Laurent2000EffectsOC,
  title={Effects of caffeine on muscle glycogen utilization and the neuroendocrine axis during exercise.},
  author={Didier Laurent and Klaus Schneider and William K Prusaczyk and Cheri Franklin and Stephen M. Vogel and Martin Krss{\'a}k and Kitt Falk Petersen and Harold W Goforth and Gerald I Shulman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2000},
  volume={85 6},
  pages={2170-5}
}
To examine the effect of caffeine ingestion on muscle glycogen utilization and the neuroendocrine axis during exercise, we studied 20 muscle glycogen-loaded subjects who were given placebo or caffeine (6 mg/kg) in a double blinded fashion 90 min before cycling for 2 h at 65% of their maximal oxygen consumption. Exercise-induced glycogen depletion in the thigh muscle was noninvasively measured by means of 13C nuclear magnetic resonance spectroscopy (NMR) spectroscopy, and plasma concentrations… CONTINUE READING

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