Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain.

@article{Irmak2003EffectsOC,
  title={Effects of caffeic acid phenethyl ester and alpha-tocopherol on reperfusion injury in rat brain.},
  author={Mehmet Kemal Irmak and Ersin Fadillioglu and Sadik Sogut and Hasan Erdogan and Mukaddes Gulec and Mustafa Ozer and Murat Yağmurca and M Engin Gozukara},
  journal={Cell biochemistry and function},
  year={2003},
  volume={21 3},
  pages={283-9}
}
Oxygen-derived free radicals have been implicated in the pathogenesis of cerebral injury after ischaemia-reperfusion. Caffeic acid phenethyl ester (CAPE), an active component of propolis extract, exhibits antioxidant properties. The purpose of the present study was to investigate the effects of ischaemia and subsequent reperfusion on rat brain and to investigate the effects of two free radical scavengers, CAPE and alpha-tocopherol, on this in vivo model of cerebral injury. Ischaemia was induced… CONTINUE READING

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