Effects of cadmium ions on the initial stage of translation and the cell death in mouse liver.


OBJECTIVE To evaluate in vivo and in vitro effects of cadmium ions on the activities of mice liver tRNA(Leu)and leucyl-tRNA synthetase and on the type of liver cells death. MATERIAL AND METHODS White laboratory mice were intoxicated by intraperitoneal injection of cadmium chloride solution (1.6 mg cadmium ions/1 kg of body weigh). Total tRNAs were… (More)