Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers
@article{Strain2000EffectsOB, title={Effects of buprenorphine versus buprenorphine/naloxone tablets in non-dependent opioid abusers}, author={E. Strain and K. Stoller and S. Walsh and G. Bigelow}, journal={Psychopharmacology}, year={2000}, volume={148}, pages={374-383} }
Abstract Rationale: Buprenorphine is an opioid agonist-antagonist under development in the United States as a sublingual medication for treatment of opioid dependence. Buprenorphine may be abused; therefore, tablets combining buprenorphine with naloxone have been developed with the intent of reducing the abuse risk in people physically dependent upon opioids. The characteristics and abuse potential of buprenorphine and buprenorphine/naloxone tablets in non-dependent opioid abusers have not been… CONTINUE READING
Paper Mentions
Interventional Clinical Trial
Buprenorphine is a medication used to treat opioid addiction, but individuals who use this
drug are at risk of abusing it. A buprenorphine and naloxone combination may reduce the… Expand
Conditions | Opioid-Related Disorders |
---|---|
Intervention | Drug |
92 Citations
Acute effects of intramuscular and sublingual buprenorphine and buprenorphine/naloxone in non-dependent opioid abusers
- Medicine
- Psychopharmacology
- 2010
- 20
Blockade of hydromorphone effects by buprenorphine/naloxone and buprenorphine
- Medicine
- Psychopharmacology
- 2002
- 48
Self-Administration of Intravenous Buprenorphine and the Buprenorphine/Naloxone Combination by Recently Detoxified Heroin Abusers
- Medicine
- Journal of Pharmacology and Experimental Therapeutics
- 2002
- 91
- Highly Influenced
- PDF
Pharmacokinetics and Subjective Effects of Sublingual Buprenorphine, Alone or in Combination with Naloxone
- Medicine
- Clinical pharmacokinetics
- 2004
- 69
- PDF
The clinical efficacy and abuse potential of combination buprenorphine–naloxone in the treatment of opioid dependence
- Medicine
- Expert opinion on pharmacotherapy
- 2009
- 46
References
SHOWING 1-10 OF 33 REFERENCES
Buprenorphine and naloxone combinations: the effects of three dose ratios in morphine-stabilized, opiate-dependent volunteers
- Medicine
- Psychopharmacology
- 1999
- 100
- PDF
Effects of buprenorphine and naloxone in morphine-stabilized opioid addicts.
- Medicine
- Drug and alcohol dependence
- 1998
- 108
- PDF
Buprenorphine and naloxone interactions in methadone maintenance patients
- Medicine
- Biological Psychiatry
- 1997
- 51
Buprenorphine: dose-related blockade of opioid challenge effects in opioid dependent humans.
- Medicine
- The Journal of pharmacology and experimental therapeutics
- 1988
- 211
Buprenorphine alone and in combination with naloxone in non-dependent humans.
- Medicine
- Drug and alcohol dependence
- 1992
- 63
- PDF
Buprenorphine vs methadone maintenance treatment for concurrent opioid dependence and cocaine abuse.
- Medicine
- Archives of general psychiatry
- 1997
- 304
A clinical trial of buprenorphine: Comparison with methadone in the detoxification of heroin addicts
- Medicine
- Clinical pharmacology and therapeutics
- 1988
- 262
Use of buprenorphine in the treatment of opiate addiction. I. Physiologic and behavioral effects during a rapid dose induction
- Medicine
- Clinical pharmacology and therapeutics
- 1989
- 96
Sublingual versus subcutaneous buprenorphine in opiate abusers
- Medicine
- Clinical pharmacology and therapeutics
- 1989
- 97
Subjective and physiologie effects of intravenous buprenorphine in humans
- Medicine
- Clinical pharmacology and therapeutics
- 1993
- 95