Corpus ID: 32553338

Effects of brotizolam on cardiovascular functions and autonomic nervous system.

@article{Kushiku1986EffectsOB,
  title={Effects of brotizolam on cardiovascular functions and autonomic nervous system.},
  author={K. Kushiku and H. Morishita and T. Furukawa and H. Kitagawa and K. Ueno and H. Kohei},
  journal={Arzneimittel-Forschung},
  year={1986},
  volume={36 3A},
  pages={
          552-9
        }
}

K. Kushiku, H. Morishita, +3 authors H. Kohei

Published 1986

Medicine

Arzneimittel-Forschung

The effects of brotizolam (2-bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno(3,2-fl-1,2,4-triazolo [4,3-a]-1,4-diazepine, We 941, Lendormin), a new thieno-triazolo-diazepine, on the heart, hemodynamic functions and the autonomic nervous system were investigated in rats, guinea pigs, rabbits, cats and dogs: In pentobarbital anesthetized dogs, 1 or 5 mg/kg brotizolam administered intravenously, decreased heart rate, with a frequency-dependent prolongation of the intervals and heightening of the T… CONTINUE READING

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