Effects of brief and long maternal separations on the HPA axis activity and the performance of rats on context and tone fear conditioning.

@article{Guijarro2007EffectsOB,
  title={Effects of brief and long maternal separations on the HPA axis activity and the performance of rats on context and tone fear conditioning.},
  author={Jussara Z Guijarro and Paula Ayako Tiba and Tatiana Lima Ferreira and Suzi Emiko Kawakami and Maria Gabriela M Oliveira and Deborah Suchecki},
  journal={Behavioural brain research},
  year={2007},
  volume={184 2},
  pages={101-8}
}
Previous studies show that early life events result in neurobehavioural alterations that may be either beneficial or detrimental to the stress response. Given the close relationship between corticosterone secretion and mnemonic processes, the purpose of the present study was to investigate the effects of brief (BMS, 15 min) and long maternal separations (LMS, 180 min) on memory tasks in adult rats, assessed by context and tone fear conditioning. At adulthood, males were evaluated for… CONTINUE READING

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