Effects of botulinum toxin B on refractory detrusor overactivity: a randomized, double-blind, placebo controlled, crossover trial.

@article{Ghei2005EffectsOB,
  title={Effects of botulinum toxin B on refractory detrusor overactivity: a randomized, double-blind, placebo controlled, crossover trial.},
  author={Maneesh Ghei and Barry H Maraj and Raymond Russell Miller and Senthil Nathan and Caoihme O'Sullivan and ClareJ. Fowler and Priyanshi R. Shah and James G Malone-Lee},
  journal={The Journal of urology},
  year={2005},
  volume={174 5},
  pages={
          1873-7; discussion 1877
        }
}
PURPOSE Open, observational studies of intradetrusor injections of botulinum toxin for detrusor overactivity have reported beneficial effects. We tested the efficacy and safety of botulinum toxin B for the treatment of the overactive bladder in a randomized, double-blind, placebo controlled crossover trial. MATERIALS AND METHODS A total of 20 patients 18 to 80 years old with detrusor overactivity unresponsive to oral antimuscarinic agents participated in the study. They were injected with… CONTINUE READING

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