Effects of bisphosphonates on matrix mineralization.

  title={Effects of bisphosphonates on matrix mineralization.},
  author={Georges Boivin and Pierre Jean Meunier},
  journal={Journal of musculoskeletal & neuronal interactions},
  volume={2 6},
Bone strength is determined not only by the volume of bone tissue and the microarchitectural organization of this bone, but also by the degree of mineralization of bone matrix. The mineralization process consists of a primary deposition of mineral substance on the calcification front, followed by a slow and progressive increase of the mineral deposition named secondary mineralization. In osteoporosis, there is a negative imbalance between bone resorption and bone formation, resulting in bone… CONTINUE READING


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