Effects of bisphenol A on gap junctions in HaCaT cells as mediated by the estrogen receptor pathway

  title={Effects of bisphenol A on gap junctions in HaCaT cells as mediated by the estrogen receptor pathway},
  author={Qi Zhang and Shuang-hu Wu and Lu Liu and Xiaohong Hou and Jianjun Jiang and Xuetao Wei and Weidong Hao},
  journal={Journal of Applied Toxicology},
  pages={271 - 281}
Bisphenol A (BPA) is widely used as the raw material for the production of plastics and paper products. People can be exposed to BPA through dermal contact, particularly for cashiers in contact with thermal paper every day. BPA is a known endocrine disruptor that has been shown to be carcinogenic. Many tumors show weak gap junctional intercellular communication (GJIC) function. The aim of this study was to investigate the effects and possible mechanisms of BPA's action on GJIC of human HaCaT… 
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