Effects of bilateral striatal 6-OHDA lesions on circadian rhythms in the rat: a radiotelemetric study.

@article{Ben2000EffectsOB,
  title={Effects of bilateral striatal 6-OHDA lesions on circadian rhythms in the rat: a radiotelemetric study.},
  author={V Ben and Bernard Bruguerolle},
  journal={Life sciences},
  year={2000},
  volume={67 13},
  pages={1549-58}
}
The present work aims to document, in a previously described animal model of Parkinson (double bilateral striatal injection of 6-OHDA), the possible modifications of circadian markers rhythms i.e. temperature (T), heart rate (H) and locomotor activity (A) registered continuously by telemetry, in order to evaluate a possible perturbation of the circadian rythmicity. H, T and A were measured by radiotelemetry after surgical implantation of the transmitters (Data Sciences). After a recovery period… CONTINUE READING

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