Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats.

@article{Indolfi2001EffectsOB,
  title={Effects of balloon injury on neointimal hyperplasia in streptozotocin-induced diabetes and in hyperinsulinemic nondiabetic pancreatic islet-transplanted rats.},
  author={Ciro Indolfi and Daniele Torella and Luigi Cavuto and Alberto M. Davalli and Cinzia Coppola and Giovanni Esposito and Maria Vincenza Carriero and Antonio Rapacciuolo and Emilio Di Lorenzo and Eugenio Stabile and Cinzia Perrino and Alaide Chieffo and Francesca Pardo and Massimo Chiariello},
  journal={Circulation},
  year={2001},
  volume={103 24},
  pages={2980-6}
}
BACKGROUND The mechanisms of increased neointimal hyperplasia after coronary interventions in diabetic patients are still unknown. METHODS AND RESULTS Glucose and insulin effects on in vitro vascular smooth muscle cell (VSMC) proliferation and migration were assessed. The effect of balloon injury on neointimal hyperplasia was studied in streptozotocin-induced diabetic rats with or without adjunct insulin therapy. To study the effect of balloon injury in nondiabetic rats with hyperinsulinemia… CONTINUE READING

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Diabetes and the cardiologists: a call to action.J

  • Friesinger GC, Gavin JA
  • Am Coll Cardiol
  • 2000

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