Effects of baicalein on apoptosis, cell cycle arrest, migration and invasion of osteosarcoma cells.

@article{Zhang2013EffectsOB,
  title={Effects of baicalein on apoptosis, cell cycle arrest, migration and invasion of osteosarcoma cells.},
  author={Yi Zhang and Lu Song and Lin Cai and Renxiong Wei and Hao Hu and Wei Jin},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2013},
  volume={53},
  pages={
          325-33
        }
}
Baicalein is a bioactive flavonoid that is widely used in ancient China. However, its effects on the most common primary malignant bone tumor, osteosarcoma, remain unknown. In the present study, we investigated the effects of baicalein in osteosarcoma cells. Our results indicate baicalein might be an efficacious anti-osteosarcoma drug. We found that baicalein could inhibit cell proliferation in a time- and dose-dependent manner. Additionally, we demonstrated that baicalein promotes osteosarcoma… CONTINUE READING

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