Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse

@article{Haney2010EffectsOB,
  title={Effects of baclofen and mirtazapine on a laboratory model of marijuana withdrawal and relapse},
  author={Margaret Haney and Carl L. Hart and Suzanne K Vosburg and Sandra D. Comer and Stephanie Collins Reed and Ziva D Cooper and Richard W. Foltin},
  journal={Psychopharmacology},
  year={2010},
  volume={211},
  pages={233-244}
}
Only a small percentage of individuals seeking treatment for their marijuana use achieves sustained abstinence, suggesting more treatment options are needed. We investigated the effects of baclofen (study 1) and mirtazapine (study 2) in a human laboratory model of marijuana intoxication, withdrawal, and relapse. In study 1, daily marijuana smokers (n = 10), averaging 9.4 (±3.9) marijuana cigarettes/day, were maintained on placebo and each baclofen dose (60, 90 mg/day) for 16 days. In study 2… CONTINUE READING
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