Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.

Abstract

PURPOSE To investigate in vivo the survival of retinal ganglion cells (RGC) 4 to 14 days after optic nerve (ON) transection alone or in combination wih a single intraocular injection of neurotrophin-4 (NT-4), neurotrophin-3 (NT-3), or brain-derived neurotrophic factor (BDNF). METHODS In adult rats, RGCs were labeled with fluorogold (FG) applied to their… (More)

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@article{PeinadoRamn1996EffectsOA, title={Effects of axotomy and intraocular administration of NT-4, NT-3, and brain-derived neurotrophic factor on the survival of adult rat retinal ganglion cells. A quantitative in vivo study.}, author={P Peinado-Ram{\'o}n and Maria Jo{\~a}o Salvador and Mar{\'i}a Paz Villegas-P{\'e}rez and Manuel Vidal-Sanz}, journal={Investigative ophthalmology & visual science}, year={1996}, volume={37 4}, pages={489-500} }