Effects of atropine, acepromazine, meperidine, and xylazine on gastroesophageal sphincter pressure in the dog.

@article{Strombeck1985EffectsOA,
  title={Effects of atropine, acepromazine, meperidine, and xylazine on gastroesophageal sphincter pressure in the dog.},
  author={Donald R. Strombeck and David Harrold},
  journal={American journal of veterinary research},
  year={1985},
  volume={46 4},
  pages={
          963-5
        }
}
Gastroesophageal sphincter (GES) pressure was 47.9 +/- 1.2 mm of Hg in nontreated dogs. Treatment with atropine, acepromazine, and xylazine reduced GES pressure to 13.2 +/- 2.03, 18.6 +/- 2.14, and 11.7 +/- 1.19 mm of Hg, respectively. Treatment with meperidine resulted in phasic contractions with minimum and maximum pressures of 27.9 +/- 4.55 and 98.9 +/- 9.16 mm of Hg, respectively. Drugs used in anesthetic procedures can reduce GES pressure in dogs.