Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain.

@article{Mohammadi2013EffectsOA,
  title={Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain.},
  author={Mohammad taghi Mohammadi and Reza Amini and Zahra Jahanbakhsh and Shahnaz Shekarforoush},
  journal={Iranian biomedical journal},
  year={2013},
  volume={17 3},
  pages={152-7}
}
BACKGROUND It is well known that the development of brain oxidative stress is one of the most serious complications of arterial hypertension that evokes brain tissue damage. The aim of this study was to examine the effects of atorvastatin treatment (20 mg/kg/day), as an antioxidant, to prevent the brain tissue oxidative stress in the hypertensive (HTN) rats. METHODS Experiments were performed in four groups of rats (n = 5 each group): sham, sham-treated, HTN and HTN treated. Rats were made… CONTINUE READING