Effects of ascorbic acid and alpha-tocopherol on arsenic-induced oxidative stress.

@article{Ramanathan2002EffectsOA,
  title={Effects of ascorbic acid and alpha-tocopherol on arsenic-induced oxidative stress.},
  author={Kadirvel Ramanathan and B S Balakumar and Chinnakkannu Panneerselvam},
  journal={Human & experimental toxicology},
  year={2002},
  volume={21 12},
  pages={675-80}
}
Arsenic is an ubiquitous element in the environment causing oxidative burst in the exposed individuals leading to tissue damage. Antioxidants have long been known to reduce the free radical-mediated oxidative stress. Therefore, the present study was designed to determine whether supplementation of alpha-tocopherol (400 mg/kg body weight) and ascorbic acid (200 mg/kg body weight) to arsenic-intoxicated rats (100 ppm in drinking water) for 30 days affords protection against the oxidative stress… CONTINUE READING
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