Effects of arsenic and UVB on normal human cultured keratinocytes: impact on apoptosis and implication on photocarcinogenesis.

@article{Chen2005EffectsOA,
  title={Effects of arsenic and UVB on normal human cultured keratinocytes: impact on apoptosis and implication on photocarcinogenesis.},
  author={Po-Hung Chen and C C E Lan and M Chiou and Ming-Chu Hsieh and Gwo-Shing Chen},
  journal={Chemical research in toxicology},
  year={2005},
  volume={18 2},
  pages={139-44}
}
Inorganic arsenic is an environmental toxin and a human carcinogen. Being a co-mutagen, arsenic enhances carcinogenesis of ultraviolet irradiation on the mouse skin. Apoptosis, a well-regulated cell death process, is essential for cell development and tissue homeostasis. Dysregulation of apoptosis will lead to various kinds of pathological conditions, such as cancers. The purpose of this study is to investigate the apoptotic effect induced by the interactions of arsenic and UVB on cultured… CONTINUE READING

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