• Corpus ID: 12249812

Effects of arotinoids upon murine embryonal carcinoma cells.

  title={Effects of arotinoids upon murine embryonal carcinoma cells.},
  author={Michael I. Sherman and Maria Paternoster and Makoto Mark Taketo},
  journal={Cancer research},
  volume={43 9},
Five arotinoids have been compared with all-trans- and 13-cisretinoic acids for their ability to promote differentiation of cells from murine embryonal carcinoma line Nulli-SCC1. Ro-13-7410, which contains a terminal carboxylic acid residue, and Ro-14-9572, the sodium sulfinate derivative, are potent inducers of differentiation. The sodium sulfonate derivative, Ro-14-3899, is somewhat less active, whereas the ethyl sulfone (Ro-15-1570) and Ro-15-0778, an arotinoid lacking a terminal group, have… 

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