Effects of apolipoprotein A gene polymorphisms on lipoprotein (a) concentrations in Japanese.

1. Elevated plasma lipoprotein (a) (Lp(a)) concentrations have been correlated with an increased risk of premature cardiovascular disease. The plasma Lp(a) concentration is quantitatively heritable and the apolipoprotein (Apo) A gene is known as a major locus-determining Lp(a) concentration. 2. The aim of the present study was to evaluate the genetic effect… CONTINUE READING