Effects of antiviral therapy for patients with inflammatory bowel disease and a positive intestinal biopsy for cytomegalovirus.

@article{Jones2015EffectsOA,
  title={Effects of antiviral therapy for patients with inflammatory bowel disease and a positive intestinal biopsy for cytomegalovirus.},
  author={Andrea Ferguson Jones and Jeffrey D McCurdy and Edward Vincent Loftus and David Bruining and Felicity T Enders and Jill M. Killian and Thomas Smyrk},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2015},
  volume={13 5},
  pages={
          949-55
        }
}
BACKGROUND & AIMS Cytomegalovirus (CMV) is an opportunistic pathogen; documented tissue involvement of patients with inflammatory bowel disease (IBD) is associated with adverse outcomes. We quantified the density of CMV inclusions in biopsy specimens from patients with IBD and assessed their response to antiviral therapy. METHODS In a case-control study, we identified all small bowel and colon biopsy specimens collected from 1111 patients with IBD that had been submitted to the Department of… CONTINUE READING
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