Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes.

@article{Pearson1973EffectsOA,
  title={Effects of antithymocyte and antimacrophage sera on the survival of mice infected with Listeria monocytogenes.},
  author={Leonard D Pearson and J W Osebold},
  journal={Infection and immunity},
  year={1973},
  volume={7 3},
  pages={479-86}
}
Antisera prepared in rabbits against purified mouse thymocytes (antithymocyte serum; ATS) and peritoneal macrophages (antimacrophage serum; AMS) were injected intraperitoneally into Balb/c mice infected with the bacterium Listeria monocytogenes. When administered near the initiation of infection, the ATS significantly decreased the survival time of the animals and increased the mortality rate. When ATS was administered 6 days after a sublethal dose of L. monocytogenes had been inoculated, an… CONTINUE READING