• DOI:10.1016/j.bbr.2011.06.026
Corpus ID: 34634953

Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats

@article{Calzavara2011EffectsOA,
  title={Effects of antipsychotics and amphetamine on social behaviors in spontaneously hypertensive rats},
  author={M. Calzavara and R. Levin and W. Medrano and V. Almeida and V. Ab{\'i}lio},
  journal={Behavioural Brain Research},
  year={2011},
  volume={225},
  pages={15-22}
}

M. Calzavara, R. Levin, +2 authors V. Abílio

Published 2011

Psychology, Medicine

Behavioural Brain Research

We have recently reported that spontaneously hypertensive rats (SHRs) exhibit a deficit in contextual fear conditioning that is specifically reversed by antipsychotic and potentiated by psychostimulants and other manipulations thought to produce schizophrenia-like states in rodents. Based on these findings, we suggested that this deficit in fear conditioning could be used as an experimental model of emotional processing impairments observed in schizophrenia. This strain has also been suggested… CONTINUE READING

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