Effects of antioxidant vitamins on newborn and placental traits in gestations at high altitude: comparative study in high and low altitude native sheep.

@article{Parraguez2011EffectsOA,
  title={Effects of antioxidant vitamins on newborn and placental traits in gestations at high altitude: comparative study in high and low altitude native sheep.},
  author={V{\'i}ctor H. Parraguez and Miljenko A Atlagich and Oscar Florencio Araneda and Carlos Guti{\'e}rrez Garc{\'i}a and Andr{\'e}s Mu{\~n}oz and M J Palomo de Los Reyes and Bessie Urquieta},
  journal={Reproduction, fertility, and development},
  year={2011},
  volume={23 2},
  pages={285-96}
}
The present study evaluated the hypothesis that the effects of hypoxia on sheep pregnancies at high altitude (HA) are mediated by oxidative stress and that antioxidant vitamins may prevent these effects. Both HA native and newcomer ewes were maintained at an altitude of 3,589 m during mating and pregnancy. Control low altitude (LA) native ewes were maintained at sea level. Half of each group received daily oral supplements of vitamins C (500 mg) and E (350 IU) during mating and gestation. Near… CONTINUE READING