Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson's disease.

Abstract

The effect of pretreating cell suspensions of embryonic rat ventral mesencephala (VM) with antioxidant combinations on the survival of dopaminergic (DA) neurons was studied in vitro and following transplantation into the unilateral 6-hydroxydopamine (6-OHDA)-lesioned rat model of Parkinson's disease. The in vitro experiments examined the effects of two… (More)

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@article{Love2002EffectsOA, title={Effects of antioxidant pretreatment on the survival of embryonic dopaminergic neurons in vitro and following grafting in an animal model of Parkinson's disease.}, author={R. Malcolm Love and Richard L Branton and Jenny Karlsson and Pia Brundin and Declan Clarke}, journal={Cell transplantation}, year={2002}, volume={11 7}, pages={653-62} }