Effects of antineoplastic agents on wound healing in mice.

@article{Cohen1975EffectsOA,
  title={Effects of antineoplastic agents on wound healing in mice.},
  author={Steven A. Cohen and Henry L. Gabelnick and Randall K. Johnson and Abraham Goldin},
  journal={Surgery},
  year={1975},
  volume={78 2},
  pages={238-44}
}
The influence of antineoplastic agents on wound healing was evaluated in an experimental model employing surgical incisions in the skin of mice. A single injection in the therapeutic dose range of various clinically active antitumor agents was administered immediately following operation and the breaking strength of skin wounds was measured 3, 7, and 21 days later. Vincristine and methotrexate decreased wound strength at 3 days but not on days 7 or 21. Actinomycin D interfered with early phases… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Cytotoxic Drugs and Wound Repair

2014
View 3 Excerpts
Highly Influenced

Reconstructive surgery in immunocompromised patients: evaluation and therapy

GMS Interdisciplinary plastic and reconstructive surgery DGPW • 2015
View 3 Excerpts

Postoperative infections: prevention and management.

Critical care nursing clinics of North America • 2012
View 1 Excerpt

Similar Papers

Loading similar papers…