Corpus ID: 22421802

Effects of antihistamines on wound healing.

@article{Bairy1991EffectsOA,
  title={Effects of antihistamines on wound healing.},
  author={K. Laxminarayana Bairy and Chamallamudi Mallikarjuna Rao and K Vrns Ramesh and D. R. Kulkarni},
  journal={Indian journal of experimental biology},
  year={1991},
  volume={29 4},
  pages={
          398-9
        }
}
  • K. Laxminarayana Bairy, Chamallamudi Mallikarjuna Rao, +1 author D. R. Kulkarni
  • Published 1991
  • Biology, Medicine
  • Indian journal of experimental biology
  • Role of antihistamines (H1 and H2 blockers) in wound healing by utilizing incision and dead space wound models in albino rats was investigated. H1 blockers (mepyramine and promethazine) were found to decrease breaking strength of 10 day old dermal incision wounds and collagen content (as hydroxyproline) and breaking strength of granulation tissue harvested over tubular implant. On the other hand H2 blockers (Cimetidine and ranitidine) did not alter the above parameters. The findings that H1… CONTINUE READING

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