Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression.

Abstract

Elevation of intracellular cyclic adenosine 3':5' monophosphate (cAMP) inhibits interleukin 2 (IL-2)-stimulated proliferation of a murine cytotoxic cell clone, CT6. The effects of antiproliferative dosages of stable cAMP-derivative, 8-bromoadenosine 3':5'-monophosphate (8-Br-cAMP), on steady state mRNA expression stimulated by IL-2 was examined. IL-2… (More)

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Cite this paper

@article{Farrar1987EffectsOA, title={Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression.}, author={William L. Farrar and Stuart Wyn Evans and Ulf R{\"{u}diger Rapp and John L. Cleveland}, journal={Journal of immunology}, year={1987}, volume={139 6}, pages={2075-80} }